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DPF3 抗体 (Middle Region)

DPF3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775708
发货至: 中国
  • 抗原 See all DPF3 抗体
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 31
    • 23
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, 豚鼠, 马, Cow, 犬
    宿主
    • 46
    克隆类型
    • 46
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DPF3 antibody is un-conjugated
    应用范围
    • 39
    • 18
    • 13
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    KDGFTSESTT LEALLRGEGV EKKVDAREEE SIQEIQRVLE NDENVEEGNE
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against DPF3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DPF3
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 357 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Theodorou, Speletas, Mamara, Papachristopoulou, Lazou, Scorilas, Katsantoni: "Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia." in: PLoS ONE, Vol. 8, Issue 10, pp. e76155, (2013) (PubMed).

    Hoyal, Kammerer, Roth, Reneland, Marnellos, Kiechle, Schwarz-Boeger, Griffiths, Ebner, Rehbock, Nelson, Braun: "Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases." in: Journal of carcinogenesis, Vol. 4, pp. 13, (2005) (PubMed).

  • 抗原
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    别名
    DPF3 (DPF3 产品)
    别名
    BAF45C antibody, CERD4 antibody, 2810403B03Rik antibody, 6530402L11Rik antibody, C78788 antibody, cer-d4 antibody, si:ch211-268e23.1 antibody, wu:fj43h12 antibody, double PHD fingers 3 antibody, D4, zinc and double PHD fingers, family 3 antibody, DPF3 antibody, Dpf3 antibody, dpf3 antibody
    背景
    DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.
    Alias Symbols: CERD4, FLJ14079
    Protein Interaction Partner: SMARCA4, SMARCA2, RELA, NFKB1, SMARCD1, SMARCC1, SMARCB1, ESRRA,
    Protein Size: 357
    分子量
    40 kDa
    基因ID
    8110
    NCBI登录号
    NM_012074, NP_036206
    UniProt
    Q92784
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