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TARDBP 抗体

TARDBP 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, IHC (p), IF (cc), FACS 宿主: 兔 Monoclonal 6C6 unconjugated
产品编号 ABIN6945140
发货至: 中国
  • 抗原 See all TARDBP 抗体
    TARDBP (TAR DNA Binding Protein (TARDBP))
    适用
    • 95
    • 57
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    人, 小鼠, 大鼠, 斑马鱼
    宿主
    • 98
    • 13
    • 1
    克隆类型
    • 92
    • 20
    单克隆
    标记
    • 59
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    This TARDBP antibody is un-conjugated
    应用范围
    • 81
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    • 13
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠, 斑马鱼
    纯化方法
    Purified by Protein A.
    免疫原
    Human TDP43 between 250-350 amino acids
    克隆位点
    6C6
    亚型
    IgG
    Top Product
    Discover our top product TARDBP Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    TARDBP (TAR DNA Binding Protein (TARDBP))
    别名
    TDP43 (TARDBP 产品)
    别名
    TARDBP antibody, TDP43 antibody, DKFZp459I2127 antibody, tardbp antibody, ALS10 antibody, TDP-43 antibody, 1190002A23Rik antibody, C85084 antibody, Tdp43 antibody, wu:fb77f02 antibody, wu:fc52g10 antibody, TAR DNA binding protein antibody, Tardbp protein antibody, TAR DNA binding protein L homeolog antibody, TAR DNA-binding protein 43-like antibody, TARDBP antibody, tardbp antibody, tardbp.L antibody, Tardbp antibody, LOC100621383 antibody
    背景

    Synonyms: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, POLR2A

    Background: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.

    基因ID
    23435
    UniProt
    Q13148
    途径
    Positive Regulation of Peptide Hormone Secretion
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