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TARDBP 抗体

KO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854799
发货至: 中国
  • 抗原 See all TARDBP 抗体
    TARDBP (TAR DNA Binding Protein (TARDBP))
    适用
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    宿主
    • 102
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    克隆类型
    • 93
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    多克隆
    标记
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    This TARDBP antibody is un-conjugated
    应用范围
    • 85
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to TARDBP (TAR DNA binding protein)
    TARDBP antibody
    纯化方法
    Affinity purified by Protein A.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product TARDBP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: H1299 , HeLa , mouse brain

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    TARDBP (TAR DNA Binding Protein (TARDBP))
    别名
    TAR DNA binding protein (TARDBP 产品)
    别名
    TARDBP antibody, TDP43 antibody, DKFZp459I2127 antibody, tardbp antibody, ALS10 antibody, TDP-43 antibody, 1190002A23Rik antibody, C85084 antibody, Tdp43 antibody, wu:fb77f02 antibody, wu:fc52g10 antibody, TAR DNA binding protein antibody, Tardbp protein antibody, TAR DNA binding protein L homeolog antibody, TAR DNA-binding protein 43-like antibody, TARDBP antibody, tardbp antibody, tardbp.L antibody, Tardbp antibody, LOC100621383 antibody
    背景
    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

    Cellular Localization: Nucleus
    分子量
    45 kDa
    基因ID
    23435
    UniProt
    Q13148
    途径
    Positive Regulation of Peptide Hormone Secretion
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