我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

TARDBP 抗体 (C-Term)

Cited in 1 publication. The 兔多克隆 anti-TARDBP antibody (ABIN2780849) specifically detects TARDBP in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马和豚鼠 samples.

IHC

IHC

Host: Rabbit Target Name: TARDBP Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1. (TARDBP 抗体 (C-Term))

Rabbit Anti-TARDBP antibody Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell Antibody Concentration: 4. (TARDBP 抗体 (C-Term))

IHC

6 images

(1 reference)

产品编号 ABIN2780849

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TARDBP 抗体 (C-Term) (ABIN2780849)

抗原

See all TARDBP 抗体

TARDBP (TAR DNA Binding Protein (TARDBP))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This TARDBP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product TARDBP Primary Antibody

抗原表位
15

13

13

12

8

8

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
C-Term

原理

TARDBP Antibody - C-terminal region

序列

MGMLASQQNQ SGPSGNNQNQ GNMQREPNQA FGSGNNSYSG SNSGAAIGWG

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against TARDBP. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human TARDBP
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibody
TARDBP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
KD Validated TARDBP 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4730 unconjugated Recombinant Antibody

anti-TAR DNA Binding Protein (TARDBP) antibody
KO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibody
TARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 126-260) antibody
TARDBP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7F9A6 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38942-100UG

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Polymenidou, Lagier-Tourenne, Hutt, Huelga, Moran, Liang, Ling, Sun, Wancewicz, Mazur, Kordasiewicz, Sedaghat, Donohue, Shiue, Bennett, Yeo, Cleveland: "Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43." in: Nature neuroscience, Vol. 14, Issue 4, pp. 459-68, (2011) (PubMed).
抗原

TARDBP (TAR DNA Binding Protein (TARDBP))

别名

TARDBP

背景

Background Information: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Gene Name: TAR DNA binding protein
Alternative Symbols: ALS10, TDP-43
Protein Name: TAR DNA-binding protein 43

分子量

45kDa

基因ID

23435

NCBI登录号

NP_031401

UniProt

Q13148

途径

Positive Regulation of Peptide Hormone Secretion