Laminin gamma 1 抗体
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- 抗原 See all Laminin gamma 1 (LAMC1) 抗体
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Laminin gamma 1 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
- 交叉反应 （详细）
- Human. Mouse.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Murine EHS laminin preparation
- 克隆位点
- A5
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product LAMC1 Primary Antibody
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anti-Laminin, gamma 1 (LAMC1) antibody
LAMC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1300-1609) antibodyLAMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1442-1552) antibodyLAMC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL3195 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Normal colon or carcinomas.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
- 别名
- LAMC1 (LAMC1 产品)
- 别名
- lamb2 antibody, Lamb2 antibody, B2e antibody, sly antibody, LAMB2 antibody, putative laminin gamma-1 chain antibody, laminin subunit gamma 1 antibody, laminin, gamma 1 antibody, Smp_163810 antibody, lamc1 antibody, Lamc1 antibody, LAMC1 antibody
- 背景
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LAMB2, LAMC1, Laminin B2 chain, Laminin gamma 1, Laminin gamma 1 chain,Laminin, gamma 1 (LAMC1)
Cellular localisation: Basement membrane - 分子量
- 210kDa
- 基因ID
- 3915, 609663
- UniProt
- P11047, Q5VYE7, Q6NVY8
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