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Laminin gamma 1 产品

(Laminin, gamma 1 (LAMC1))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis. [provided by RefSeq, Aug 2011].

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Featured Laminin gamma 1 Categories

Laminin gamma 1 抗体

High quality antibodies with extensive validation data.

Laminin gamma 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Laminin gamma 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Laminin gamma 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7258846
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7268186
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
  • (5)
Cat. No. ABIN5692889
Quantity 100 μg
Datasheet Datasheet

Recommended Laminin gamma 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957392
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN585495
Quantity 96 tests
Datasheet Datasheet

Recommended Laminin gamma 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309130
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093542
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132431
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Laminin gamma 1 Products

Fu, Hu, Dang, Chang, Du, Wu, Gao: "Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels." in: Scientific reports, Vol. 6, pp. 27020, (2018) (PubMed).

Sun, Wang, Guo, Xiao, Sun, Yin, Meng, Sui, Zhao, Guo, Wang, Xu, Liu, Li, Lu, Peng: "Acellular Cauda Equina Allograft as Main Material Combined with Biodegradable Chitin Conduit for Regeneration of Long-Distance Sciatic Nerve Defect in Rats." in: Advanced healthcare materials, Vol. 7, Issue 17, pp. e1800276, (2018) (PubMed).

Liang, Li, Wang, Wu, Cai, Cui, Yang, Ya: "Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart." in: Development, growth & differentiation, Vol. 56, Issue 4, pp. 276-92, (2014) (PubMed).

Chen, Wang, Liu, Fang, Tan, Zhou, Zhou, Lv: "Highly effective ex vivo gene manipulation to study kidney development using self-complementary adenoassociated viruses." in: TheScientificWorldJournal, Vol. 2014, pp. 682189, (2014) (PubMed).

Gao, Zheng, Cai, Yao, Wang, Zhang, Wang: "Comparison of morphology and biocompatibility of acellular nerve scaffolds processed by different chemical methods." in: Journal of materials science. Materials in medicine, Vol. 25, Issue 5, pp. 1283-91, (2014) (PubMed).

Lin, Li, Su: "Three dimensional chitosan scaffolds influence the extra cellular matrix expression in Schwann cells." in: Materials science & engineering. C, Materials for biological applications, Vol. 42, pp. 474-8, (2014) (PubMed).

Liu, Lu, Li, Wei, Li: "Engineering blood vessels through micropatterned co-culture of vascular endothelial and smooth muscle cells on bilayered electrospun fibrous mats with pDNA inoculation." in: Acta biomaterialia, Vol. 11, pp. 114-25, (2014) (PubMed).

Wu, Chen, Guo, He, Hu: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, (2014) (PubMed).

Zhu, Xu, Yuan, Guo, Liu: "Transcriptome sequencing reveals differences between primary and secondary hair follicle-derived dermal papilla cells of the Cashmere goat (Capra hircus)." in: PLoS ONE, Vol. 8, Issue 9, pp. e76282, (2013) (PubMed).

Guo, Xu, He, Liang, Duan, Li: "Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-? expression and inhibition of PI3K/Akt pathway." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 56, pp. 436-42, (2013) (PubMed).

Synonyms and alternative names related to Laminin gamma 1

putative laminin gamma-1 chain (Smp_163810), laminin subunit gamma 1 (lamc1), laminin, gamma 1 (Lamc1), laminin subunit gamma 1 (Lamc1), laminin, gamma 1 (lamc1), laminin subunit gamma 1 (LAMC1), B2e, lamb2, Lamb2, LAMB2, sly

Protein level used designations for Laminin gamma 1

  • laminin gamma-1 chain
  • laminin subunit gamma-1
  • S-LAM gamma
  • S-laminin subunit gamma
  • laminin B2 chain
  • laminin-1 subunit gamma
  • laminin-10 subunit gamma
  • laminin-11 subunit gamma
  • laminin-2 subunit gamma
  • laminin-3 subunit gamma
  • laminin-4 subunit gamma
  • laminin-6 subunit gamma
  • laminin-7 subunit gamma
  • laminin-8 subunit gamma
  • laminin-9 subunit gamma
  • shortstop
  • shp
  • sleepy
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