Lamin 抗体
(Lamin)
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012].
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Recommended Lamin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
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Validations
Cat. No.
ABIN533372
Quantity
500 μg
Datasheet
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Reactivity
Human
Application
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Cat. No.
ABIN533353
Quantity
500 μg
Datasheet
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Application
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Validations
Cat. No.
ABIN1824170
Quantity
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Datasheet
Datasheet
Synonyms and alternative names related to Lamin
lamin B2 (lmnb2), im:7142331, lamin, wu:fb94e05, wu:fb95e12, wu:fc15d06, wu:fc49h03Protein level used designations for Lamin
- fc15d06
- lamin-B2
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