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LAP 产品

(Leucine Aminopeptidase (LAP))
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10\;11)(p13\;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].

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Featured LAP Categories

LAP 抗体

High quality antibodies with extensive validation data.

LAP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

LAP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LAP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1859614
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1862838
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB, ELISA, IF
Validations
Cat. No. ABIN458923
Quantity 1 mg
Datasheet Datasheet

Recommended LAP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957444
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957445
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN770907
Quantity 96 tests
Datasheet Datasheet

Recommended LAP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390799
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390802
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3010450
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LAP Products

Wang, Xue, Li, Yang, He, Zhang, Zhang, Tang: "In Vivo Two-Photon Fluorescence Imaging of the Activity of the Inflammatory Biomarker LTA4H in a Mouse Pneumonia Model." in: Analytical chemistry, Vol. 90, Issue 10, pp. 6020-6027, (2019) (PubMed).

Agapova, Stephenson, Manary, Weisz, Tarr, Mkakosya, Maleta, Shulman, Manary, Shaikh: "Detection of low-concentration host mRNA transcripts in Malawian children at risk for environmental enteropathy." in: Journal of pediatric gastroenterology and nutrition, Vol. 56, Issue 1, pp. 66-71, (2013) (PubMed).

Synonyms and alternative names related to LAP

leucine aminopeptidase (PVX_118180), leucine aminopeptidase (CpipJ_CPIJ002841), leucine aminopeptidase (lap), leucine aminopeptidase (pepA), leucine aminopeptidase (NAEGRDRAFT_78195), leucine aminopeptidase (TP04_0561), leucine aminopeptidase (BBOV_II004450), leucine aminopeptidase, putative (PKH_126020), leucine aminopeptidase (NAEGRDRAFT_82309), phosphatidylinositol binding clathrin assembly protein (PICALM), phosphatidylinositol binding clathrin assembly protein (Picalm), 18.m06372, CALM, Calm, CLTH, DDBDRAFT_0218188, DDBDRAFT_0231024, DDB_0218188, DDB_0231024, LAP

Protein level used designations for LAP

  • leucine aminopeptidase
  • clathrin assembly lymphoid myeloid leukemia protein
  • phosphatidylinositol-binding clathrin assembly protein
  • clathrin-assembly lymphoid leukemia protein
  • clathrin-assembly lymphoid myeloid leukemia protein
  • rCALM
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