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Laminin gamma 1 抗体 (AA 1300-1609)

LAMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7268186
发货至: 中国
  • 抗原 See all Laminin gamma 1 (LAMC1) 抗体
    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1300-1609
    适用
    • 45
    • 24
    • 19
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 37
    • 9
    • 5
    克隆类型
    • 36
    • 15
    多克隆
    标记
    • 35
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Laminin gamma 1 antibody is un-conjugated
    应用范围
    • 30
    • 20
    • 16
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    LAMC1 Rabbit pAb
    序列
    IDQKLKDYED LREDMRGKEL EVKNLLEKGK TEQQTADQLL ARADAAKALA EEAAKKGRDT LQEANDILNN LKDFDRRVND NKTAAEEALR KIPAINQTIT EANEKTREAQ QALGSAAADA TEAKNKAHEA ERIASAVQKN ATSTKAEAER TFAEVTDLDN EVNNMLKQLQ EAEKELKRKQ DDADQDMMMA GMASQAAQEA EINARKAKNS VTSLLSIIND LLEQLGQLDT VDLNKLNEIE GTLNKAKDEM KVSDLDRKVS DLENEAKKQE AAIMDYNRDI EEIMKDIRNL EDIRKTLPSG CFNTPSIEKP
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1609 of human LAMC1 (NP_002284.3).
    亚型
    IgG
    Top Product
    Discover our top product LAMC1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
    别名
    LAMC1 (LAMC1 产品)
    别名
    lamb2 antibody, Lamb2 antibody, B2e antibody, sly antibody, LAMB2 antibody, putative laminin gamma-1 chain antibody, laminin subunit gamma 1 antibody, laminin, gamma 1 antibody, Smp_163810 antibody, lamc1 antibody, Lamc1 antibody, LAMC1 antibody
    背景
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma. Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.,LAMC1,LAMB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,Neurodegenerative Diseases,LAMC1
    分子量
    177kDa
    基因ID
    3915
    UniProt
    P11047
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