Lamin A/C 产品
(Lamin A/C (LMNA))
Categories
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012].
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Featured Lamin A/C Categories
Lamin A/C 抗体
High quality antibodies with extensive validation data.
Lamin A/C ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Lamin A/C 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Lamin A/C 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (11)
- (32)
Cat. No.
ABIN3020785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (4)
- (8)
Cat. No.
ABIN2854943
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN7254833
Quantity
200 μL
Datasheet
Datasheet
Recommended Lamin A/C ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957374
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968180
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968181
Quantity
96 tests
Datasheet
Datasheet
Recommended Lamin A/C 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1309507
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123712
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3093600
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Lamin A/C Products
: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." in: Viruses, Vol. 13, Issue 2, (2021) (PubMed).: "Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97." in: Viruses, Vol. 13, Issue 7, (2021) (PubMed).
: "The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus." in: Cells, Vol. 10, Issue 11, (2021) (PubMed).
: "Resveratrol inhibits viability and induces apoptosis in the small‑cell lung cancer H446 cell line via the PI3K/Akt/c‑Myc pathway." in: Oncology reports, Vol. 44, Issue 5, pp. 1821-1830, (2021) (PubMed).
: "MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation." in: Frontiers in physiology, Vol. 11, pp. 510, (2020) (PubMed).
: "Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit." in: Theranostics, Vol. 9, Issue 9, pp. 2526-2540, (2020) (PubMed).
: "Non-proliferative neurogenesis in human periodontal ligament stem cells." in: Scientific reports, Vol. 9, Issue 1, pp. 18038, (2019) (PubMed).
: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)." in: Oncotarget, Vol. 7, Issue 47, pp. 76667-76683, (2018) (PubMed).
: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).
Synonyms and alternative names related to Lamin A/C
lamin A/C (LMNA), lamin A (Lmna), Lamin (Lam), lamin A/C (Lmna), lamin A (lmna), lamin A/C L homeolog (lmna.L), lamin A/C (lmna), lamin-L(III)-like (LMINA), 74/76, 2459, cb948, CDCD1, cdcd1, CDDC, cddc, CG6944, CMD1A, cmd1a, CMT2B1, cmt2b1, D5, Dhe, Dm, Dm(0), Dm0, Dm1, Dm2, Dmel\\CG6944, DmLamin, DmO, Dmo, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], DM[[O]], Dm[[o]], EMD2, emd2, fk66d12, FPL, fpl, FPLD, fpld, FPLD2, HGPS, hgps, IDC, idc, jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, LAM, lam, Lam(Dm0), lamDm0, Lam Dm[[0]], LamDm[[0]], lamDm[[0]], LamDm[[o]], lamin, Lamin-A, lamin-L(III)-like, lamin Dm0, Lamin Dm[[0]], lamin Dm[[0]], Lam[[Dm0]], LDP1, ldp1, LFP, lfp, LGMD1B, lgmd1b, LMN1, lmn1, lmna-A, LMNC, lmnc, LMNL1, misg, nlam, PRO1, pro1, wu:fk66d12Protein level used designations for Lamin A/C
- 70 kDa lamin
- lamin
- lamin A/C-like 1
- prelamin-A/C
- renal carcinoma antigen NY-REN-32
- lamin C
- lamin-A/C
- B-type lamin
- CG6944-PA
- CG6944-PB
- CG6944-PC
- Lam-PA
- Lam-PB
- Lam-PC
- Lamin-B
- LaminDm
- LaminDm0
- alpha-Lamin
- intermediate filament-like lamina
- lamin A
- lamin B
- lamin D
- lamin D[[0]]
- lamin D[[m]]0
- lamin D[[o]]
- lamin Dm0
- lamin Dm[[0]]
- lamin Dmo
- lethal(2)25Ec
- misguided
- misrouted
- n-lamin
- nuclear lamin
- lamin C2
- lamin-A
- lamin A/C
- lamin-A/C-like
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