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EGFR 抗体

Name: EGFR 抗体
Brand: antibodies-online
SKU: ABIN6937132
Availability: OutOfStock

EGFR 适用: 人 FACS, IP, AP, ProA, Act, in vivo 宿主: 小鼠 Monoclonal B1D8 unconjugated

产品编号 ABIN6937132

发货至: 中国

Datasheet as PDF

抗原 See all EGFR 抗体

EGFR (Epidermal Growth Factor Receptor (EGFR))
适用
772

320

310

26

26

24

20

14

9

3

2

2

1

1

1

1

1

1
人
宿主
610

166

14

11

4

1
小鼠
Compatible Secondaries
克隆类型
575

226

2
单克隆
标记
399

63

31

29

29

29

29

27

27

25

22

14

10

10

10

10

10

5

4

4

4

4

4

1

1

1

1

1

1

1
This EGFR antibody is un-conjugated
应用范围
540

254

145

133

122

101

91

85

81

42

37

34

33

18

9

8

6

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Affinity Purification (AP), Proliferation Assay (ProA), Activation (Act), In vivo Studies (in vivo)

特异性

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF'induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

无交叉反应

小鼠, 大鼠

交叉反应（详细）

Human. Does not react with Mouse or Rat.

纯化方法

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

免疫原

Microsomes from A431 cells.

克隆位点

B1D8

亚型

IgG2a kappa

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anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893), (Mutant) antibody
EGFR 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5G9B5 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 豚鼠, 兔, Cat, 驴, 山羊, Hamster, 绵羊, Avian WB 宿主: 山羊 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 960-1060) antibody
EGFR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Known_Application: Affinity Purification (For coupling, order Ab without BSA), Blocks Ligand-induced Activation of EGFR, Inhibits Proliferation of A431 cells (Order Ab without sodium azide), Arrests Tumor Growth in vivo (Order Ab without BSA &Azide), Immunoprecipitation (1-2 μg/500 μg protein lysate), Flow Cytometry (1-2 μg/million cells), Optimal dilution for a specific application should be determined.
Positive_Control: A431 cells, Breast or Bladder cancer.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

储存液

Azide free

储存条件

-20 °C,-80 °C

储存方法

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

有效期

24 months
抗原

EGFR (Epidermal Growth Factor Receptor (EGFR))

别名

EGFR (EGFR 产品)

别名

C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody

背景

Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5,EGFR (Epidermal Growth Factor Receptor)
Cellular localisation: Cell surface

分子量

~170kDa (wild type) and ~145kDa (vIII variant)

基因ID

1956, 488293

UniProt

P00533

途径

NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins