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PPP1R13B 抗体 (AA 901-1090) (Biotin)

PPP1R13B 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN674381
发货至: 中国
  • 抗原 See all PPP1R13B 抗体
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 901-1090
    适用
    • 51
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 51
    • 1
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP1R13B antibody is conjugated to Biotin
    应用范围
    • 38
    • 24
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ASPP1
    亚型
    IgG
    Top Product
    Discover our top product PPP1R13B Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    别名
    ASPP1 (PPP1R13B 产品)
    别名
    ASPP1 antibody, p53BP2-like antibody, p85 antibody, AI449786 antibody, AW545810 antibody, Tp53bp2 antibody, Trp53bp2 antibody, protein phosphatase 1 regulatory subunit 13B antibody, protein phosphatase 1, regulatory subunit 13B antibody, protein phosphatase 1 regulatory subunit 13B L homeolog antibody, protein phosphatase 1, regulatory subunit 13Bb antibody, protein phosphatase 1, regulatory (inhibitor) subunit 13B antibody, PPP1R13B antibody, Ppp1r13b antibody, ppp1r13b.L antibody, ppp1r13bb antibody, ppp1r13b antibody
    背景

    Synonyms: p53BP2 like, p85, PPP1R13B, apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51.

    Background: iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51.

    基因ID
    23368
    UniProt
    Q96KQ4
    途径
    p53 Pathway
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