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PPP1R13B 产品

(Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008].

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Featured PPP1R13B Categories

PPP1R13B 抗体

High quality antibodies with extensive validation data.

PPP1R13B ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PPP1R13B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPP1R13B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7189519
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7144480
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2565797
Quantity 100 μg
Datasheet Datasheet

Recommended PPP1R13B ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1122285
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1122284
Quantity 96 tests
Datasheet Datasheet

Recommended PPP1R13B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565206
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089479
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135552
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PPP1R13B Products

Xie, Yang, Chi, Yang, Wang, Xu: "Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study." in: Chinese journal of cancer, Vol. 36, Issue 1, pp. 15, (2017) (PubMed).

Agirre, Román-Gómez, Jiménez-Velasco, Garate, Montiel-Duarte, Navarro, Vázquez, Zalacain, Calasanz, Heiniger, Torres, Minna, Prósper: "ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia." in: Oncogene, Vol. 25, Issue 13, pp. 1862-70, (2006) (PubMed).

Liu, Lu, Zhong: "ASPP--Apoptotic specific regulator of p53." in: Biochimica et biophysica acta, Vol. 1756, Issue 1, pp. 77-80, (2005) (PubMed).

Bergamaschi, Samuels, Zhong, Lu: "Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation." in: Oncogene, Vol. 24, Issue 23, pp. 3836-41, (2005) (PubMed).

Synonyms and alternative names related to PPP1R13B

protein phosphatase 1 regulatory subunit 13B (PPP1R13B), protein phosphatase 1, regulatory subunit 13B (Ppp1r13b), protein phosphatase 1 regulatory subunit 13B L homeolog (ppp1r13b.L), protein phosphatase 1, regulatory subunit 13Bb (ppp1r13bb), protein phosphatase 1 regulatory subunit 13B (ppp1r13b), protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b), protein phosphatase 1 regulatory subunit 13B (Ppp1r13b), AI449786, ASPP1, AW545810, p53BP2-like, p85, Tp53bp2, Trp53bp2

Protein level used designations for PPP1R13B

  • apoptosis-stimulating of p53 protein 1
  • apoptosis-stimulating protein of p53, 1
  • protein phosphatase 1 regulatory subunit 13B
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B
  • apoptosis-stimulating protein of p53
  • apoptosis-stimulating of p53 protein 1-like
  • transformation related protein 53 binding protein 2
  • tumor protein p53 binding protein, 2
  • tumor protein p53-binding protein, 2
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