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PPM1G 产品

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))

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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010].

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Featured PPM1G Categories

PPM1G 抗体

High quality antibodies with extensive validation data.

PPM1G 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPM1G 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1500378
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7246652
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF, ICC
Validations
  • (2)
  • (1)
Cat. No. ABIN533783
Quantity 100 μL
Datasheet Datasheet

Recommended PPM1G ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951685
Quantity 96 tests
Datasheet Datasheet

Recommended PPM1G 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315916
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315918
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124674
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PPM1G Products

Richter, Dayaram, Gilmartin, Ganji, Pemmasani, Van Der Key, Shohet, Donehower, Kumar: "WIP1 phosphatase as a potential therapeutic target in neuroblastoma." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115635, (2015) (PubMed).

Khoronenkova, Dianova, Ternette, Kessler, Parsons, Dianov: "ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage." in: Molecular cell, Vol. 45, Issue 6, pp. 801-13, (2012) (PubMed).

Hutten, Prescott, James, Riesenberg, Boulon, Lam, Lamond: "An intranucleolar body associated with rDNA." in: Chromosoma, Vol. 120, Issue 5, pp. 481-99, (2011) (PubMed).

Ryan, Khleborodova, Pan, Ryan: "Small molecule activators of pre-mRNA 3' cleavage." in: RNA (New York, N.Y.), Vol. 15, Issue 3, pp. 483-92, (2009) (PubMed).

Suh, Kim, Kim: "PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)." in: FEBS letters, Vol. 580, Issue 26, pp. 6100-4, (2006) (PubMed).

Flajolet, Rakhilin, Wang, Starkova, Nuangchamnong, Nairn, Greengard: "Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 16006-11, (2003) (PubMed).

Synonyms and alternative names related to PPM1G

protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (Ppm1g), protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G), protein phosphatase, Mg2+/Mn2+ dependent, 1G (Ppm1g), AI385652, Fin13, PP2CG, PP2CGAMMA, PPP2CG

Protein level used designations for PPM1G

  • PP2C-gamma
  • fibroblast growth factor inducible 13
  • fibroblast growth factor-inducible protein 13
  • protein phosphatase 1C
  • protein phosphatase 1G
  • protein phosphatase 2C isoform gamma
  • protein phosphatase magnesium-dependent 1 gamma
  • PP2C, gamma
  • protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
  • protein phosphatase 2, catalytic subunit, gamma isoform
  • protein phosphatase 2C gamma isoform
  • MCPP
  • magnesium-dependent calcium inhibitable phosphatase
  • protein phosphatase 1B
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