PPP1R13B 抗体 (Middle Region)
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北京 101111
Quick Overview for PPP1R13B 抗体 (Middle Region) (ABIN2783179)
抗原
See all PPP1R13B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PPP1R13B Antibody - middle region
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序列
- EFDLVQRIIY EVEDPSKPND EGITPLHNAV CAGHHHIVKF LLDFGVNVNA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PPP1R13B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPP1R13B
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47979-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
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别名
- PPP1R13B
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背景
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Background Information: PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Gene Name: Protein phosphatase 1, regulatory subunit 13B
Alternative Symbols: p85, ASPP1, p53BP2-like
Protein Name: Apoptosis-stimulating of p53 protein 1
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分子量
- 119kDa
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基因ID
- 23368
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NCBI登录号
- NP_056131
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UniProt
- Q96KQ4
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途径
- p53 Pathway
抗原
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