NPC1 抗体 (AA 591-620)
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- 抗原 See all NPC1 抗体
- NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
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抗原表位
- AA 591-620
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-620 amino acids from the Central region of human NPC1.
- 克隆位点
- RB33297
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NPC1 Primary Antibody
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anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody
NPC1 适用: 人 ELISA, WB, IHC, FACS 宿主: 小鼠 Monoclonal 8D10G3 unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibodyNPC1 适用: 人 ELISA, WB, IHC 宿主: 小鼠 Monoclonal 8D10B6 unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibodyNPC1 适用: 人 ELISA, WB, IHC, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 591-620) antibodyNPC1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 23-269) antibodyNPC1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 151-250) antibodyNPC1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) antibodyNPC1 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 1230-1278) antibodyNPC1 适用: 人, 小鼠, Hamster WB, IHC, IF, IP, IEM 宿主: 兔 Polyclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (Internal Region) antibodyVerified NPC1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Niemann-Pick Disease, Type C1 (NPC1) (C-Term) antibodyNPC1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- NPC1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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- 抗原
- NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
- 别名
- NPC1 (NPC1 产品)
- 别名
- NPC antibody, 9130221N23Rik antibody, Gm243 antibody, Cdig2 antibody, im:7149020 antibody, wu:fb53a12 antibody, wu:fc29a12 antibody, A430089E03Rik antibody, C85354 antibody, D18Ertd139e antibody, D18Ertd723e antibody, lcsd antibody, nmf164 antibody, spm antibody, NPC intracellular cholesterol transporter 1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, Niemann-Pick disease, type C1 antibody, Niemann-Pick C1 protein antibody, NPC1 antibody, Npc1l1 antibody, Npc1 antibody, npc1 antibody, LOC579887 antibody
- 背景
- This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
- 分子量
- 142167
- 基因ID
- 4864
- NCBI登录号
- NP_000262
- UniProt
- O15118
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