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NPC1 抗体 (AA 591-620)

NPC1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031998
发货至: 中国
  • 抗原 See all NPC1 抗体
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    抗原表位
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 591-620
    适用
    • 46
    • 19
    • 14
    • 2
    宿主
    • 41
    • 5
    • 2
    克隆类型
    • 34
    • 14
    多克隆
    标记
    • 21
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NPC1 antibody is un-conjugated
    应用范围
    • 30
    • 27
    • 20
    • 14
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 591-620 from the human protein was used as the immunogen for this NPC1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NPC1 Primary Antibody
  • 应用备注
    Titration of the NPC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the NPC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
    别名
    NPC1 (NPC1 产品)
    别名
    NPC antibody, 9130221N23Rik antibody, Gm243 antibody, Cdig2 antibody, im:7149020 antibody, wu:fb53a12 antibody, wu:fc29a12 antibody, A430089E03Rik antibody, C85354 antibody, D18Ertd139e antibody, D18Ertd723e antibody, lcsd antibody, nmf164 antibody, spm antibody, NPC intracellular cholesterol transporter 1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, Niemann-Pick disease, type C1 antibody, Niemann-Pick C1 protein antibody, NPC1 antibody, Npc1l1 antibody, Npc1 antibody, npc1 antibody, LOC579887 antibody
    背景
    This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
    UniProt
    O15118
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