DCC 抗体 (Middle Region)
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- 抗原 See all DCC 抗体
- DCC (Deleted in Colorectal Carcinoma (DCC))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DCC antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- DCC antibody was raised against the middle region of DCC
- 纯化方法
- Affinity purified
- 免疫原
- DCC antibody was raised using the middle region of DCC corresponding to a region with amino acids PIGQMHPPHGSVTPQKNSNLLVIIVVTVGVITVLVVVIVAVICTRRSSAQ
- Top Product
- Discover our top product DCC Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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DCC Blocking Peptide, catalog no. 33R-7153, is also available for use as a blocking control in assays to test for specificity of this DCC antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DCC antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- DCC (Deleted in Colorectal Carcinoma (DCC))
- 别名
- DCC (DCC 产品)
- 别名
- CRC18 antibody, CRCR1 antibody, IGDCC1 antibody, MRMV1 antibody, DCC antibody, zdcc antibody, C030036D22Rik antibody, Igdcc1 antibody, xdcc antibody, XDCCa antibody, dcca-A antibody, Dcc antibody, DCC netrin 1 receptor antibody, deleted in colorectal carcinoma antibody, netrin receptor DCC antibody, DCC antibody, dcc antibody, Dcc antibody, LOC100712666 antibody
- 背景
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
- 分子量
- 158 kDa (MW of target protein)
- 途径
- Regulation of Cell Size
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