DCC 抗体 (Middle Region)
-
- 抗原 See all DCC 抗体
- DCC (Deleted in Colorectal Carcinoma (DCC))
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DCC antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- PIGQMHPPHG SVTPQKNSNL LVIIVVTVGV ITVLVVVIVA VICTRRSSAQ
- 预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DCC. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DCC
-
anti-Deleted in Colorectal Carcinoma (DCC) (C-Term) antibody
DCC 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) antibodyDCC 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 162-178) antibodyDCC 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (Internal Region) antibodyDCC 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 1048-1082), (C-Term) antibodyDCC 适用: 人 WB 宿主: 兔 Polyclonal RB51762 unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 1079-1128) antibodyDCC 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (Internal Region) antibodyDCC 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 162-178), (N-Term) antibodyDCC 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 643-670) antibodyDCC 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32203 unconjugated
anti-Deleted in Colorectal Carcinoma (DCC) (AA 642-670), (Middle Region) antibodyDCC 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1447 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- DCC (Deleted in Colorectal Carcinoma (DCC))
- 别名
- DCC (DCC 产品)
- 别名
- CRC18 antibody, CRCR1 antibody, IGDCC1 antibody, MRMV1 antibody, DCC antibody, zdcc antibody, C030036D22Rik antibody, Igdcc1 antibody, xdcc antibody, XDCCa antibody, dcca-A antibody, Dcc antibody, DCC netrin 1 receptor antibody, deleted in colorectal carcinoma antibody, netrin receptor DCC antibody, DCC antibody, dcc antibody, Dcc antibody, LOC100712666 antibody
- 背景
-
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
Alias Symbols: CRC18, CRCR1, IGDCC1
Protein Interaction Partner: UBC, ALB, BARD1, sina, UBI4, SIAH2, EIF4E3, EIF2A, EIF5A2, NTN1, RPL23, EIF2S2, EIF2B2, EIF2B4, EZR, RPS24, RPS13, RPS10, RPS6, RPS4X, RPL38, RPL28, RPL13, RPL5, PTK2, MAPK1, RPL10A, EIF3E, EIF4E, EIF2S3, EIF2B1, EIF1AX, ADORA2B, APPL1, CASP9, SIAH1, MAPK
Protein Size: 1447 - 分子量
- 158 kDa
- 基因ID
- 1630
- NCBI登录号
- NM_005215, NP_005206
- UniProt
- P43146
- 途径
- Regulation of Cell Size
-
