JAG1 抗体 (Internal Region)
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- 抗原 See all JAG1 抗体
- JAG1 (Jagged 1 (JAG1))
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抗原表位
- AA 981-1030, Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Jagged1 is a protein encoded by the JAG1 gene which is approximately 133,7 kDa. Jagged1 is localised to the plasma membrane. It is involved in signalling by Notch1, Notch2 activation and transmission of signal to the nucleus and the HIV life cycle. It is a ligand for multiple Notch receptors and may also be involved in cell-fate decisions during hematopoiesis and in the early and late stages of mammalian cardiovascular development. Jagged1 is widely expressed in adult and foetal tissues. Mutations in the JAG1 gene may result in Alagille syndrome. STJ96766 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Jagged1 protein.
- 特异性
- Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
- 产品特性
- Rabbit polyclonal to Jagged1.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Jagged1.
- 亚型
- IgG
- Top Product
- Discover our top product JAG1 Primary Antibody
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anti-Jagged 1 (JAG1) (Internal Region) antibody
JAG1 适用: 人, 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6A9B2 unconjugated
anti-Jagged 1 (JAG1) (AA 836-1047) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 809-1046) antibodyJAG1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) antibodyJAG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal J1G53-3 unconjugated
anti-Jagged 1 (JAG1) (AA 470-834) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 33-250) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 826-1084) antibodyJAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (N-Term) antibodyJAG1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (C-Term) antibodyVerified JAG1 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000 - 说明
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Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- JAG1 (Jagged 1 (JAG1))
- 别名
- Jagged1 (JAG1 产品)
- 别名
- AGS antibody, AHD antibody, AWS antibody, CD339 antibody, HJ1 antibody, JAGL1 antibody, ABE2 antibody, Gsfabe2 antibody, Htu antibody, Ozz antibody, Ser-1 antibody, JAG1 antibody, jag3 antibody, cb243 antibody, jag1 antibody, sb:cb243 antibody, serrateC antibody, jagged1 antibody, serrate antibody, serrate-1 antibody, x-serrate-1 antibody, jagged 1 antibody, jagged 1b antibody, jagged 1a antibody, jagged 1 L homeolog antibody, JAG1 antibody, Jag1 antibody, jag1 antibody, jag1b antibody, jag1a antibody, jag1.L antibody
- 分子量
- 140 kDa
- 基因ID
- 182
- UniProt
- P78504
- 途径
- Notch Signaling, Stem Cell Maintenance
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