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JAG1 抗体

The 小鼠 单克隆 anti-JAG1 antibody (Clone J1G53-3) (ABIN1169436) specifically detects JAG1 in WB, IHC, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1169436
发货至: 中国
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Quick Overview for JAG1 抗体 (ABIN1169436)

抗原

See all JAG1 抗体
JAG1 (Jagged 1 (JAG1))

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This JAG1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

J1G53-3
  • 原理

    anti-Jagged-1 (human), mAb (J1G53-3)

    特异性

    Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot.

    产品特性

    Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human Jagged-1.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    JAG1 (Jagged 1 (JAG1))

    别名

    Jagged-1

    背景

    Alternate Names/Synonyms: Protein Jagged-1, CD339, JAG1

    Product Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

    UniProt

    P78504

    途径

    Notch Signaling, Stem Cell Maintenance
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