JAG1 抗体
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北京 101111
Quick Overview for JAG1 抗体 (ABIN1169436)
抗原
See all JAG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Jagged-1 (human), mAb (J1G53-3)
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特异性
- Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot.
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产品特性
- Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human Jagged-1.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- JAG1 (Jagged 1 (JAG1))
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别名
- Jagged-1
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背景
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Alternate Names/Synonyms: Protein Jagged-1, CD339, JAG1
Product Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
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UniProt
- P78504
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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