PERK 抗体 (AA 920-1000)
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- 抗原 See all PERK (EIF2AK3) 抗体
- PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
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抗原表位
- AA 920-1000
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PERK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- PERK is a protein encoded by the EIF2AK3 gene which is approximately 125,2 kDa. PERK is localised to the endoplasmic reticulum membrane. It is involved in respiratory electron transport, apoptosis modulation and signalling and animal autophagy. It phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and a rapid reduction of translational initiation and repression of global protein synthesis. PERK is expressed in the nervous system, liver, pancreas, lung and heart. Mutations in the EIF2AK3 gene may result in Wolcott-Rallison syndrome and diversion colitis. STJ95031 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PERK protein only when phosphorylated at T981.
- 特异性
- PERK Polyclonal Antibody detects endogenous levels of PERK protein.
- 产品特性
- Rabbit polyclonal to PERK.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human PERK around the non-phosphorylation site of T981.
- 亚型
- IgG
- Top Product
- Discover our top product EIF2AK3 Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (AA 973-1114) antibody
EIF2AK3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr982) antibodyEIF2AK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr980) antibodyEIF2AK3 适用: 人, 小鼠, 大鼠, 犬, Pig WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr981) antibodyEIF2AK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (C-Term) antibodyEIF2AK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (AA 1001-1116) antibodyEIF2AK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) antibodyEIF2AK3 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (AA 115-330) antibodyEIF2AK3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (AA 665-764) antibodyEIF2AK3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (N-Term) antibodyEIF2AK3 适用: 人 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000 - 说明
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Ubiquitous. A high level expression is seen in secretory tissues.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
- 别名
- PERK (EIF2AK3 产品)
- 别名
- EIF2AK3 antibody, AI427929 antibody, Pek antibody, Perk antibody, PEK antibody, PERK antibody, WRS antibody, eukaryotic translation initiation factor 2 alpha kinase 3 antibody, EIF2AK3 antibody, Eif2ak3 antibody
- 分子量
- 125 kDa
- 基因ID
- 9451
- UniProt
- Q9NZJ5
- 途径
- Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response
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