PERK 产品
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Categories
The gene PERK, also known as EIF2AK3, plays a crucial role in cellular biology, particularly in the regulation of protein synthesis and the cellular response to stress. Dysregulation of the PERK pathway is associated with various diseases, including neurodegenerative disorders, diabetes, and cancer, making it an important target for research and potential therapeutic interventions. PERK is one of the four kinases that phosphorylate the eukaryotic translation initiation factor 2 alpha (eIF2α), which is a key component of the translation machinery in cells.
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Featured PERK Categories
PERK 抗体
High quality antibodies with extensive validation data.
PERK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PERK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PERK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441241
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
- (5)
Cat. No.
ABIN6255756
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (14)
- (3)
Cat. No.
ABIN744713
Quantity
100 μL
Datasheet
Datasheet
Recommended PERK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966610
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966609
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955664
Quantity
96 tests
Datasheet
Datasheet
Recommended PERK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5570058
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352504
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3092214
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PERK Products
: "A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer." in: Oncogene, Vol. 37, Issue 10, pp. 1308-1325, (2019) (PubMed).: "Opposite Regulation of CHOP and GRP78 and Synergistic Apoptosis Induction by Selenium Yeast and Fish Oil via AMPK Activation in Lung Adenocarcinoma Cells." in: Nutrients, Vol. 10, Issue 10, (2019) (PubMed).
: "Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 84-92, (2019) (PubMed).
: "Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism." in: Alcoholism, clinical and experimental research, Vol. 43, Issue 8, pp. 1682-1694, (2019) (PubMed).
: "Functional Characterization of a Novel Truncating Mutation in Lamin A/C Gene in a Family with a Severe Cardiomyopathy with Conduction Defects." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 4, pp. 1559-1577, (2018) (PubMed).
: "GRP78 silencing enhances hyperoxia-induced alveolar epithelial cell apoptosis via CHOP pathway." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1493-1501, (2018) (PubMed).
: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).
: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
: "SWNHs (Single-Wall Carbon Nanohorns) Supervises Endoplasmic Reticulum (ER) Stress in Hepatocellular Carcinoma." in: Journal of nanoscience and nanotechnology, Vol. 18, Issue 10, pp. 6740-6745, (2018) (PubMed).
: "Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination." in: Scientific reports, Vol. 6, pp. 32710, (2018) (PubMed).
Synonyms and alternative names related to PERK
eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3), eukaryotic translation initiation factor 2 alpha kinase 3 (Eif2ak3), AI427929, EIF2AK3, Pek, PEK, Perk, PERK, WRSProtein level used designations for PERK
- eukaryotic translation initiation factor 2-alpha kinase 3
- eukaryotic translation initiation factor 2-alpha kinase 3-like
- PRKR-like endoplasmic reticulum kinase
- pancreatic eIF2-alpha kinase
- eukaryotic translation initiation factor 2 alpha kinase 3
- hsPEK
- pancreatic EIF2-alpha kinase
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- Peptide F
- Peptidase E
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- Permeability Glycoprotein
- Peropsin
- Peroxidase
- Peroxidase 3
- Peroxidase 66
- Peroxidase 70
- Peroxidasin
- Peroxiredoxin
- Peroxiredoxin (tsaA)
- Peroxiredoxin 1
- Peroxiredoxin 2
- Peroxiredoxin 3
- Peroxiredoxin 4
- Peroxiredoxin 5
- Peroxiredoxin 6
- Peroxisomal Bifunctional Enzyme
- Peroxisomal Biogenesis Factor 5-Like
- PERP
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- Pertussis Toxin
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