AXL 抗体 (pTyr691)
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- 抗原 See all AXL 抗体
- AXL (AXL Receptor tyrosine Kinase (AXL))
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抗原表位
- AA 630-710, pTyr691
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AXL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Axl is a protein encoded by the AXL gene which is approximately 98,3 kDa. Axl is localised to the cell membrane. It is involved in the GPCR pathway, ERK signalling, actin nucleation by ARP-WASP complex and activation of cAMP-dependent PKA. This protein falls under the Tyro3-Axl-Mer receptor tyrosine kinase subfamily. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6. Axl is expressed in primary colon tumors but weakly expressed in normal colon tissue. Mutations in the AXL gene may result in lymphocytic choriomeningitis, femoral neuropathy and Borna disease. STJ90939 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous Axl protein which only binds about Y691 when Y691 is phosphorylated.
- 特异性
- Phospho-Axl (Y691) Polyclonal Antibody detects endogenous levels of Axl protein only when phosphorylated at Y691.
- 产品特性
- Rabbit polyclonal to Phospho-Axl (Y691).
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Axl around the phosphorylation site of Y691.
- 亚型
- IgG
- Top Product
- Discover our top product AXL Primary Antibody
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anti-AXL Receptor tyrosine Kinase (AXL) (AA 30-140) antibody
AXL 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6C8 unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) antibodyAXL 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) antibodyAXL 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (AA 13-44) antibodyAXL 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (AA 151-250) antibodyAXL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (AA 312-447) antibodyAXL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (AA 21-202) antibodyAXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (AA 1-894) antibodyAXL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) antibodyAXL 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7-00E-10 unconjugated
anti-AXL Receptor tyrosine Kinase (AXL) (C-Term) antibodyKO Validated AXL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- AXL (AXL Receptor tyrosine Kinase (AXL))
- 别名
- Axl (AXL 产品)
- 别名
- JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody
- 分子量
- 110/97 kDa
- 基因ID
- 558
- UniProt
- P30530
- 途径
- RTK signaling, Cellular Response to Molecule of Bacterial Origin
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