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E2F1 抗体 (pThr433)

E2F1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6283586
发货至: 中国
  • 抗原 See all E2F1 抗体
    E2F1 (E2F Transcription Factor 1 (E2F1))
    抗原表位
    • 25
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    AA 370-450, pThr433
    适用
    • 206
    • 99
    • 56
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
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    • 1
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    人, 小鼠
    宿主
    • 209
    • 12
    • 2
    克隆类型
    • 200
    • 23
    多克隆
    标记
    • 92
    • 17
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    This E2F1 antibody is un-conjugated
    应用范围
    • 186
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    Western Blotting (WB), ELISA
    原理
    E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, glioma, E2F mediated regulation of DNA replication and activation of BH3-only proteins. It is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. E2F-1 is expressed in the skin, pancreas and nervous system. Mutations in the E2F1 gene may result in retinoblastoma and pharyngoconjunctival fever. STJ90458 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous E2F-1 protein which only binds about T433 when T433 is phosphorylated.
    特异性
    Phospho-E2F-1 (T433) Polyclonal Antibody detects endogenous levels of E2F-1 protein only when phosphorylated at T433.
    产品特性
    Rabbit polyclonal to Phospho-E2F-1 (T433).
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human E2F-1 around the phosphorylation site of T433.
    亚型
    IgG
    Top Product
    Discover our top product E2F1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    ELISA 1:5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    E2F1 (E2F Transcription Factor 1 (E2F1))
    别名
    E2F-1 (E2F1 产品)
    别名
    CG6376 antibody, DRTF1/E2F antibody, DmE2F-1 antibody, Dmel\\CG6376 antibody, Dp antibody, E(Sev-CycE)3A antibody, E(var)3-93E antibody, E(var)3-95E antibody, E(var)93E antibody, E2F antibody, E2F-1 antibody, E2F1 antibody, E2f1 antibody, Evar(3)164 antibody, dE2F antibody, dE2F1 antibody, dE2f antibody, dE2f1 antibody, de2f1 antibody, def21 antibody, drosE2F1 antibody, e2f antibody, e2f1 antibody, l(3)07172 antibody, l(3)j3B1 antibody, l(3)j3C2 antibody, l(3)rM729 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, mKIAA4009 antibody, xE2F antibody, ATE2FB antibody, E2F TRANSCRIPTION FACTOR-1 E2F1 antibody, E2F transcription factor 1 antibody, E2FB antibody, E2FB TRANSCRIPTION FACTOR antibody, E2F transcription factor 1 antibody, E2F transcription factor 1 L homeolog antibody, E2f1 antibody, E2F1 antibody, e2f1.L antibody
    分子量
    47 kDa
    基因ID
    1869
    UniProt
    Q01094
    途径
    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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