TET2 抗体 (Internal Region)
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- 抗原 See all TET2 抗体
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TET2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- TET2 Antibody detects endogenous levels of total TET2.
- 预测反应
- Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TET2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TET2 Primary Antibody
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anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibody
TET2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5H8C7 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5H8B3 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyVerified TET2 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1-300) antibodyTET2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 21F11 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyRecent TET2 适用: 小鼠, 大鼠 ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (N-Term) antibodyTET2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
- 别名
- TET2 (TET2 产品)
- 别名
- KIAA1546 antibody, MDS antibody, Ayu17-449 antibody, E130014J05Rik antibody, mKIAA1546 antibody, RGD1311625 antibody, tet methylcytosine dioxygenase 2 antibody, TET2 antibody, Tet2 antibody
- 背景
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Description: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
Gene: TET2
- 分子量
- 130 kDa,133 kDa,224 kDa
- 基因ID
- 54790
- UniProt
- Q6N021
- 途径
- Warburg Effect
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