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TET2 抗体 (AA 1833-2002)

TET2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159637
发货至: 中国
  • 抗原 See all TET2 抗体
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    抗原表位
    • 17
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1833-2002
    适用
    • 47
    • 15
    • 6
    宿主
    • 41
    • 8
    • 2
    克隆类型
    • 43
    • 8
    多克隆
    标记
    • 33
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TET2 antibody is un-conjugated
    应用范围
    • 40
    • 22
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Methylcytosine dioxygenase TET2 protein (1833-2002AA)
    亚型
    IgG
    Top Product
    Discover our top product TET2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    别名
    TET2 (TET2 产品)
    别名
    KIAA1546 antibody, MDS antibody, Ayu17-449 antibody, E130014J05Rik antibody, mKIAA1546 antibody, RGD1311625 antibody, tet methylcytosine dioxygenase 2 antibody, TET2 antibody, Tet2 antibody
    背景

    Background: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.

    Aliases: FLJ20032 antibody, KIAA1546 antibody, MDS antibody, Methylcytosine dioxygenase TET2 antibody, Nbla00191 antibody, Probable methylcytosine dioxygenase TET2 antibody, Protein Ayu17 449 antibody, Tet 2 antibody, Tet methylcytosine dioxygenase 2 antibody, Tet oncogene 2 antibody, Tet oncogene family member 2 antibody, TET2 antibody, TET2_HUMAN antibody

    UniProt
    Q6N021
    途径
    Warburg Effect
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