-
- 抗原 See all KHDRBS1 抗体
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KHDRBS1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- KHDRBS1 Antibody detects endogenous levels of total KHDRBS1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KHDRBS1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product KHDRBS1 Primary Antibody
-
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) antibody
KHDRBS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) antibodyKHDRBS1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 176-275) antibodyKHDRBS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A4 unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (C-Term) antibodyKHDRBS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 156-381) antibodyKHDRBS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (N-Term) antibodyKHDRBS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 259-291) antibodyKHDRBS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB54155 unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 387-436) antibodyKHDRBS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 359-408) antibodyKHDRBS1 适用: 人, 兔, Cow, 豚鼠, 犬, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) (AA 1-381) antibodyKHDRBS1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
- 别名
- KHDRBS1 (KHDRBS1 产品)
- 别名
- Sam68 antibody, p62 antibody, p68 antibody, fj90g10 antibody, khdrbs1 antibody, wu:fa18g12 antibody, wu:fa56c01 antibody, wu:fc91b01 antibody, wu:fj90g10 antibody, zgc:113899 antibody, KHDRBS1 antibody, P62 antibody, khdrbs1l antibody, sb:cb97 antibody, wu:fb07d11 antibody, wu:fi43c05 antibody, zgc:85948 antibody, KH RNA binding domain containing, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1a antibody, KH domain containing, RNA binding, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antibody, KH domain containing, RNA binding, signal transduction associated 1b antibody, KHDRBS1 antibody, khdrbs1a antibody, khdrbs1 antibody, Khdrbs1 antibody, khdrbs1.S antibody, khdrbs1b antibody
- 背景
-
Description: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species according to (PubMed:22253824). RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). Can regulate CD44 alternative splicing in a Ras pathway-dependent manner (By similarity). In cooperation with HNRNPA1 modulates alternative splicing of BCL2L1 by promoting splicing toward isoform Bcl-X(S), and of SMN1 (PubMed:17371836, PubMed:20186123). Can regulate alternative splicing of NRXN1 and NRXN3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. In a neuronal activity-dependent manner cooperates synergistically with KHDRBS2/SLIM-1 in regulation of NRXN1 exon skipping at AS4. The cooperation with KHDRBS2/SLIM-1 is antagonistic for regulation of NXRN3 alternative splicing at AS4 (By similarity).
Gene: KHDRBS1
- 分子量
- 48 kDa
- 基因ID
- 10657
- UniProt
- Q07666
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
-
You are here:
