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KHDRBS1 抗体 (N-Term)

KHDRBS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031544
发货至: 中国
  • 抗原 See all KHDRBS1 抗体
    KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
    抗原表位
    • 15
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    N-Term
    适用
    • 43
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    人, 小鼠, 大鼠
    宿主
    • 69
    • 3
    • 1
    克隆类型
    • 70
    • 3
    多克隆
    标记
    • 42
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    This KHDRBS1 antibody is un-conjugated
    应用范围
    • 63
    • 23
    • 16
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    • 10
    • 4
    • 4
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the N-terminus of human SQSTM1 (KDDIFRIYIKEKKECRRDHR) was used as the immunogen for this p62 antibody.
    亚型
    IgG
    Top Product
    Discover our top product KHDRBS1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the p62 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
    别名
    p62 (KHDRBS1 产品)
    别名
    Sam68 antibody, p62 antibody, p68 antibody, fj90g10 antibody, khdrbs1 antibody, wu:fa18g12 antibody, wu:fa56c01 antibody, wu:fc91b01 antibody, wu:fj90g10 antibody, zgc:113899 antibody, KHDRBS1 antibody, P62 antibody, khdrbs1l antibody, sb:cb97 antibody, wu:fb07d11 antibody, wu:fi43c05 antibody, zgc:85948 antibody, KH RNA binding domain containing, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1a antibody, KH domain containing, RNA binding, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antibody, KH domain containing, RNA binding, signal transduction associated 1b antibody, KHDRBS1 antibody, khdrbs1a antibody, khdrbs1 antibody, Khdrbs1 antibody, khdrbs1.S antibody, khdrbs1b antibody
    背景
    Sequestosome-1, also known as Ubiquitin-Binding Protein p62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2(SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by binding to phosphotyrosine.p56-lck, a T-cell-specific src family tyrosine kinase with an SH2 domain, is involved in T-cell signal transduction. The International Radiation Hybrid Mapping Consortium mapped the p62 gene to chromosome 5q35. Park et al.(1995) found that the p56-lck SH2 domain binds p62 at the ser59 only when that serine is phosphorylated. Joung et al.(1996) expressed epitope-tagged p62 in Hela cells and showed that the expressed protein bound to the lck SH2 domain and that this binding was dependent on the N-terminal 50 amino acids of p62 but not on the tyrosine residue in this region.
    UniProt
    Q13501
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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