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Connexin 43/GJA1 抗体 (Internal Region)

GJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260963
发货至: 中国
  • 抗原 See all Connexin 43/GJA1 (GJA1) 抗体
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    抗原表位
    • 21
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    Internal Region
    适用
    • 135
    • 93
    • 91
    • 33
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    人, 大鼠, 小鼠
    宿主
    • 130
    • 8
    • 4
    • 1
    克隆类型
    • 134
    • 8
    多克隆
    标记
    • 83
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    This Connexin 43/GJA1 antibody is un-conjugated
    应用范围
    • 98
    • 54
    • 48
    • 29
    • 21
    • 16
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Connexin 43 / GJA1 Antibody detects endogenous levels of total Connexin 43 / GJA1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Connexin 43 / GJA1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GJA1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Zhao, Wu, Chen, Ji, Zheng: "TGF-β1 and connexin-43 expression in neurogenic bladder from rats with sacral spinal cord injury." in: Neurourology and urodynamics, (2018) (PubMed).

  • 抗原
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    别名
    GJA1 (GJA1 产品)
    背景

    Description: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).

    Gene: GJA1

    分子量
    43kDa
    基因ID
    2697
    UniProt
    P17302
    途径
    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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