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Tyrosinase-Related Protein 1 抗体

TYRP1 适用: 人, 小鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal SPM611 unconjugated
产品编号 ABIN6252894
发货至: 中国
  • 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
    Tyrosinase-Related Protein 1 (TYRP1)
    适用
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    人, 小鼠
    宿主
    • 77
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    小鼠
    克隆类型
    • 54
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    单克隆
    标记
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    This Tyrosinase-Related Protein 1 antibody is un-conjugated
    应用范围
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
    克隆位点
    SPM611
    亚型
    IgG2a kappa
    Top Product
    Discover our top product TYRP1 Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 1-2 μg/mL

    Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)

    Prediluted format: incubate for 30 min at RT (2)

    Optimal dilution of the TRP1 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    Tyrosinase-Related Protein 1 (TYRP1)
    别名
    TRP1 (TYRP1 产品)
    别名
    CAS2 antibody, CATB antibody, GP75 antibody, OCA3 antibody, TRP antibody, TRP1 antibody, TYRP antibody, b-PROTEIN antibody, LOC397853 antibody, Trypsin antibody, hm:zeh0659 antibody, tyrp1 antibody, zgc:100893 antibody, B antibody, TYRP1 antibody, tyrp-1 antibody, TRP-1 antibody, Tyrp antibody, b antibody, brown antibody, isa antibody, tyrosinase related protein 1 antibody, protease, serine 1 L homeolog antibody, tyrosinase-related protein 1b antibody, tyrosinase-related protein 1 antibody, tyrosinase-related protein 1 L homeolog antibody, tyrosinase-related protein 1a antibody, TYRP1 antibody, prss1.L antibody, tyrp1b antibody, Tyrp1 antibody, tyrp1.L antibody, tyrp1 antibody, LOC100136490 antibody, tyrp-1 antibody, tyrp1a antibody
    背景
    It reacts with a 75  kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
    基因ID
    7306
    UniProt
    P17643
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