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Tyrosinase-Related Protein 1 抗体 (AA 257-377)

TYRP1 适用: 人 ELISA, IHC, StM, Coat 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
产品编号 ABIN6940830
发货至: 中国
  • 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
    Tyrosinase-Related Protein 1 (TYRP1)
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 257-377
    适用
    • 104
    • 57
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    宿主
    • 79
    • 29
    • 1
    • 1
    小鼠
    克隆类型
    • 55
    • 53
    • 2
    单克隆
    标记
    • 53
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Tyrosinase-Related Protein 1 antibody is un-conjugated
    应用范围
    • 65
    • 39
    • 37
    • 30
    • 25
    • 22
    • 14
    • 14
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Staining Methods (StM), Coating (Coat)
    特异性
    It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
    纯化方法
    Purified by Protein A/G
    免疫原
    A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
    克隆位点
    TYRP1-3280
    亚型
    IgG2b kappa
    Top Product
    Discover our top product TYRP1 Primary Antibody
  • 应用备注

    Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human skin or melanoma tissues (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Tyrosinase-Related Protein 1 (TYRP1)
    别名
    TYRP1 (TYRP1 产品)
    别名
    CAS2 antibody, CATB antibody, GP75 antibody, OCA3 antibody, TRP antibody, TRP1 antibody, TYRP antibody, b-PROTEIN antibody, LOC397853 antibody, Trypsin antibody, hm:zeh0659 antibody, tyrp1 antibody, zgc:100893 antibody, B antibody, TYRP1 antibody, tyrp-1 antibody, TRP-1 antibody, Tyrp antibody, b antibody, brown antibody, isa antibody, tyrosinase related protein 1 antibody, protease, serine 1 L homeolog antibody, tyrosinase-related protein 1b antibody, tyrosinase-related protein 1 antibody, tyrosinase-related protein 1 L homeolog antibody, tyrosinase-related protein 1a antibody, TYRP1 antibody, prss1.L antibody, tyrp1b antibody, Tyrp1 antibody, tyrp1.L antibody, tyrp1 antibody, LOC100136490 antibody, tyrp-1 antibody, tyrp1a antibody
    分子量
    75kDa
    基因ID
    7306
    UniProt
    P17643
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