TNFSF15 抗体
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- 抗原 See all TNFSF15 抗体
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFSF15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-VEGI (VEGI/1283), Purified, BSA-free
- 产品特性
- VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Recombinant human full-length VEGI fragment
- 克隆位点
- VEGI-1283
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFSF15 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 161-251) antibody
TNFSF15 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 兔 Monoclonal VEGI-2052R unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rVEGI-1283 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal VEGI-1283 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) antibodyTNFSF15 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) antibodyTNFSF15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) antibodyTNFSF15 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow cytometry 0.5-1 μg/million cells in 0.1 mL
- Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Western blotting 1-2 μg/mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- 别名
- VEGI (TNFSF15 产品)
- 别名
- TTPAL antibody, TL1 antibody, TL1A antibody, VEGI antibody, VEGI192A antibody, Tl1 antibody, Tl1a antibody, Vegi antibody, tumor necrosis factor superfamily member 15 antibody, TNF superfamily member 15 antibody, tumor necrosis factor (ligand) superfamily, member 15 antibody, TNFSF15 antibody, Tnfsf15 antibody
- 背景
- TNF lig,-related molecule 1 (TL1A), Tumor necrosis factor (lig,) superfamily member 15 (TNFSF15), Vascular endothelial growth inhibitor 192a, Vascular endothelial growth inhibitor (VEGI), VEGI192A
- 分子量
- 22 kDa
- 基因ID
- 9966, 241382
- UniProt
- O95150
- 途径
- Positive Regulation of Endopeptidase Activity, Autophagy
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