TNFSF15 抗体
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北京 101111
Quick Overview for TNFSF15 抗体 (ABIN6941289)
抗原
See all TNFSF15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) Antibody
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特异性
- VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human VEGI fragment
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亚型
- IgG1, kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 161-251) antibody
TNFSF15 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC 宿主: 兔 Monoclonal VEGI-2052R unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC 宿主: 小鼠 Monoclonal rVEGI-1283 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 67-251) antibodyTNFSF15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-244) antibodyTNFSF15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 70-230) antibodyTNFSF15 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) antibodyTNFSF15 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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别名
- TNFSF15
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背景
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TNF ligand-related molecule 1 (TL1A), Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15), Vascular endothelial growth inhibitor 192a, Vascular endothelial growth inhibitor (VEGI), VEGI192A
Endothelial cells. Colon, intestine, Kidney, Liver, Lung, Pancreas, Placenta, spleen or prostate.
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分子量
- 22kDa
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基因ID
- 9966, 241382
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UniProt
- O95150
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途径
- Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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