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E-cadherin 抗体 (AA 381-481)

Name: E-cadherin 抗体 (AA 381-481)
SKU: ABIN614587
Availability: OutOfStock

CDH1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F4 unconjugated

Western Blotting (WB) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-481) antibody (ABIN614587) (E-cadherin 抗体 (AA 381-481))

Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-481) antibody (ABIN614587) (E-cadherin 抗体 (AA 381-481))

IHC

Immunofluorescence (IF) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-481) antibody (ABIN614587) (E-cadherin 抗体 (AA 381-481))

5 images

(1 reference)

产品编号 ABIN614587

发货至: 中国

Datasheet as PDF

抗原 See all E-cadherin (CDH1) 抗体

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
抗原表位
17

17

16

11

10

10

8

8

7

7

5

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 381-481
适用
225

96

83

18

17

12

9

9

9

6

4

4

4

4

1

1

1

1

1

1
人
宿主
193

71

7

3
小鼠
Compatible Secondaries
克隆类型
179

94

1
单克隆
标记
134

34

28

8

7

6

6

6

6

6

6

6

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This E-cadherin antibody is un-conjugated
应用范围
192

88

82

64

53

50

38

35

29

27

17

16

5

4

4

4

3

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody reacts to Cadherin 1, Type 1, E-cadherin (epithelial) (CDH1).

纯化方法

Protein A Chromatography

免疫原

Recombinant protein, CDH1 (NP_004351, 381 a.a. ~ 481 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: CDH1

克隆位点

3F4

亚型

IgG1

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anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-480) antibody
CDH1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 3F4 unconjugated

anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (C-Term) antibody
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anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 810-890) antibody
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anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody
CDH1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody
CDH1 适用: 人, 小鼠, 大鼠, Pig, 猴, 犬, 小鸡, 兔, Cow, 马, 豚鼠, Cat, 驴, 山羊, Hamster, 绵羊, Avian WB, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibody
CDH1 适用: 人 WB, IHC, IF, StM, ISt 宿主: 小鼠 Monoclonal CDH1-1525 unconjugated

anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 375-631) antibody
CDH1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 155-707) antibody
CDH1 适用: 人 WB, FACS, ELISA, IF 宿主: 小鼠 Monoclonal 9H2D3 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

PBS, pH 7.2

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C
Gauster, Maninger, Siwetz, Deutsch, El-Heliebi, Kolb-Lenz, Hiden, Desoye, Herse, Prokesch: "Downregulation of p53 drives autophagy during human trophoblast differentiation." in: Cellular and molecular life sciences : CMLS, Vol. 75, Issue 10, pp. 1839-1855, (2018) (PubMed).
抗原

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

别名

CD324 / Cadherin-1 (CDH1 产品)

别名

Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E-cadherin antibody, cdh1 antibody, si:dz180o5.2 antibody, uvo antibody, lcam antibody, E-Cad antibody, XBcad antibody, l-cam antibody, xcdh1 antibody, cdhc-A antibody, xb-cad antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, uvomorulin antibody, XB-cadherin antibody, arc-1 antibody, cd324 antibody, cdhe antibody, ecad antibody, AA960649 antibody, E-cad antibody, Ecad antibody, L-CAM antibody, Um antibody, cadherin 1 antibody, si:busm1-180o5.2 antibody, cadherin 1, type 1, E-cadherin (epithelial) antibody, cadherin 1, type 1 S homeolog antibody, CDH1 antibody, si:busm1-180o5.2 antibody, cdh1 antibody, Cdh1 antibody, cdh1.S antibody

背景

E Cadherin (CDH1) is a classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.Synonyms: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin

基因ID

999

NCBI登录号

NP_004351

UniProt

P12830

途径

WNT signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation