E-cadherin 抗体
(10 references)-
- 抗原 See all E-cadherin (CDH1) 抗体
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This E-cadherin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))
- 交叉反应
- 犬, 人, 小鼠, 大鼠, 斑马鱼
- 产品特性
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Rabbit Polyclonal antibody to E-Cadherin (cadherin 1, type 1, E-cadherin (epithelial))
E-Cadherin antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human E-Cadherin. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 401-500) antibody
CDH1 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 375-631) antibodyCDH1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (C-Term) antibodyCDH1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-480) antibodyCDH1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 810-890) antibodyCDH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibodyCDH1 适用: 人, 小鼠, 大鼠, Pig, 猴, 小鸡, 犬, 兔, Cow, 马, 豚鼠, Cat, 驴, 山羊, Hamster, 绵羊, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibodyCDH1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) antibodyCDH1 适用: 人 WB, IHC, IF, StM, ISt 宿主: 小鼠 Monoclonal CDH1-1525 unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibodyCDH1 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-481) antibodyCDH1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F4 unconjugated
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- 应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MCF-7
Validation: Comparison, KO/KD, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.29 mg/mL
- 缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury." in: Cell death & disease, Vol. 11, Issue 2, pp. 138, (2020) (PubMed).
: "Qingshen Buyang Formula Attenuates Renal Fibrosis in 5/6 Nephrectomized Rats via Inhibiting EMT and Wnt/β-Catenin Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2019, pp. 5370847, (2019) (PubMed).
: "MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway." in: EBioMedicine, Vol. 43, pp. 270-281, (2019) (PubMed).
: "Prickle1 is required for EMT and migration of zebrafish cranial neural crest." in: Developmental biology, Vol. 448, Issue 1, pp. 16-35, (2019) (PubMed).
: "H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer." in: International journal of molecular sciences, Vol. 20, Issue 16, (2019) (PubMed).
: "Effects of bradykinin on TGF‑β1‑induced epithelial‑mesenchymal transition in ARPE‑19 cells." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5878-5886, (2018) (PubMed).
: "Runx3 is a key modulator during the epithelial-mesenchymal transition of alveolar type II cells in animal models of BPD." in: International journal of molecular medicine, Vol. 40, Issue 5, pp. 1466-1476, (2018) (PubMed).
: "Low-Dose Alkylphenol Exposure Promotes Mammary Epithelium Alterations and Transgenerational Developmental Defects, But Does Not Enhance Tumorigenic Behavior of Breast Cancer Cells." in: Frontiers in endocrinology, Vol. 8, pp. 272, (2017) (PubMed).
: "Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173931, (2017) (PubMed).
: "Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells." in: PLoS ONE, Vol. 12, Issue 7, pp. e0180383, (2017) (PubMed).
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: "Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury." in: Cell death & disease, Vol. 11, Issue 2, pp. 138, (2020) (PubMed).
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- 抗原
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- 别名
- cadherin 1 (CDH1 产品)
- 别名
- Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E-cadherin antibody, cdh1 antibody, si:dz180o5.2 antibody, uvo antibody, lcam antibody, E-Cad antibody, XBcad antibody, l-cam antibody, xcdh1 antibody, cdhc-A antibody, xb-cad antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, uvomorulin antibody, XB-cadherin antibody, arc-1 antibody, cd324 antibody, cdhe antibody, ecad antibody, AA960649 antibody, E-cad antibody, Ecad antibody, L-CAM antibody, Um antibody, cadherin 1 antibody, si:busm1-180o5.2 antibody, cadherin 1, type 1, E-cadherin (epithelial) antibody, cadherin 1, type 1 S homeolog antibody, CDH1 antibody, si:busm1-180o5.2 antibody, cdh1 antibody, Cdh1 antibody, cdh1.S antibody
- 背景
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This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Cellular Localization: Cell junction , Cell membrane - 分子量
- 97 kDa
- 基因ID
- 999
- UniProt
- P12830
- 途径
- WNT signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
