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CBFA2T2 抗体 (AA 325-604)

CBFA2T2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137998
发货至: 中国
  • 抗原 See all CBFA2T2 抗体
    CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-604
    适用
    • 56
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 49
    • 6
    • 3
    • 1
    克隆类型
    • 54
    • 5
    多克隆
    标记
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBFA2T2 antibody is un-conjugated
    应用范围
    • 57
    • 22
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    GLNGGYQDEL VDHRLTEREW ADEWKHLDHA LNCIMEMVEK TRRSMAVLRR CQESDREELN YWKRRYNENT ELRKTGTELV SRQHSPGSAD SLSNDSQREF NSRPGTGYVP VEFWKKTEEA VNKVKIQAMS EVQKAVAEAE QKAFEVIATE RARMEQTIAD VKRQAAEDAF LVINEQEEST ENCWNCGRKA SETCSGCNIA RYCGSFCQHK DWERHHRLCG QNLHGQSPHG QGRPLLPVGR GSSARSADCS VPSPALDKTS ATTSRSSTPA SVTAIDTNGL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 325-604 of human CBFA2T2 (NP_005084.1).
    亚型
    IgG
    Top Product
    Discover our top product CBFA2T2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
    别名
    CBFA2T2 (CBFA2T2 产品)
    别名
    MTGR1 antibody, A430091M07 antibody, C330013D05Rik antibody, Cbfa2t2h antibody, EHT antibody, ZMYND3 antibody, p85 antibody, XETOR antibody, cbfa2t2-a antibody, CBFA2/RUNX1 translocation partner 2 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antibody, CBFA2/RUNX1 translocation partner 2 L homeolog antibody, Cbfa2t2 antibody, CBFA2T2 antibody, cbfa2t2.L antibody
    背景
    In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.,CBFA2T2,EHT,MTGR1,ZMYND3,p85,CBFA2T2
    分子量
    28 kDa/63 kDa/65 kDa/67 kDa
    基因ID
    9139
    UniProt
    O43439
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