CBFA2T2 抗体 (AA 325-604)
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- 抗原 See all CBFA2T2 抗体
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
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抗原表位
- AA 325-604
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBFA2T2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- GLNGGYQDEL VDHRLTEREW ADEWKHLDHA LNCIMEMVEK TRRSMAVLRR CQESDREELN YWKRRYNENT ELRKTGTELV SRQHSPGSAD SLSNDSQREF NSRPGTGYVP VEFWKKTEEA VNKVKIQAMS EVQKAVAEAE QKAFEVIATE RARMEQTIAD VKRQAAEDAF LVINEQEEST ENCWNCGRKA SETCSGCNIA RYCGSFCQHK DWERHHRLCG QNLHGQSPHG QGRPLLPVGR GSSARSADCS VPSPALDKTS ATTSRSSTPA SVTAIDTNGL
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 325-604 of human CBFA2T2 (NP_005084.1).
- 亚型
- IgG
- Top Product
- Discover our top product CBFA2T2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- 别名
- CBFA2T2 (CBFA2T2 产品)
- 别名
- MTGR1 antibody, A430091M07 antibody, C330013D05Rik antibody, Cbfa2t2h antibody, EHT antibody, ZMYND3 antibody, p85 antibody, XETOR antibody, cbfa2t2-a antibody, CBFA2/RUNX1 translocation partner 2 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antibody, CBFA2/RUNX1 translocation partner 2 L homeolog antibody, Cbfa2t2 antibody, CBFA2T2 antibody, cbfa2t2.L antibody
- 背景
- In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.,CBFA2T2,EHT,MTGR1,ZMYND3,p85,CBFA2T2
- 分子量
- 28 kDa/63 kDa/65 kDa/67 kDa
- 基因ID
- 9139
- UniProt
- O43439
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