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- 抗原 See all CBFA2T2 抗体
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBFA2T2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠, 小鸡, 大鼠
- 交叉反应 （详细）
- Mouse (95 %), Chicken (80 %), Rat (95 %)
- 产品特性
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Rabbit polyclonal antibody to CBFA2T2 (core-binding factor, runt domain, alpha subunit 2, translocated to, 2)
MTGR1 antibody [C1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human MTGR1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product CBFA2T2 Primary Antibody
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anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 201-304) antibody
CBFA2T2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 201-304) antibodyCBFA2T2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 1-575) antibodyCBFA2T2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 325-604) antibodyCBFA2T2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 325-604) antibodyCBFA2T2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) antibodyCBFA2T2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) antibodyCBFA2T2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 1-614) antibodyCBFA2T2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) (AA 361-410) antibodyCBFA2T2 适用: 小鼠, 大鼠, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- 别名
- CBFA2T2 (CBFA2T2 产品)
- 别名
- MTGR1 antibody, A430091M07 antibody, C330013D05Rik antibody, Cbfa2t2h antibody, EHT antibody, ZMYND3 antibody, p85 antibody, XETOR antibody, cbfa2t2-a antibody, CBFA2/RUNX1 translocation partner 2 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antibody, CBFA2/RUNX1 translocation partner 2 L homeolog antibody, Cbfa2t2 antibody, CBFA2T2 antibody, cbfa2t2.L antibody
- 背景
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In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
Cellular Localization: Nucleus - 分子量
- 67 kDa
- 基因ID
- 9139
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