CBFA2T2 抗体 (AA 325-604)
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- 抗原 See all CBFA2T2 抗体
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
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抗原表位
- AA 325-604
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBFA2T2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Protein CBFA2T2 protein (325-604AA)
- 亚型
- IgG
- Top Product
- Discover our top product CBFA2T2 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- 别名
- CBFA2T2 (CBFA2T2 产品)
- 别名
- MTGR1 antibody, A430091M07 antibody, C330013D05Rik antibody, Cbfa2t2h antibody, EHT antibody, ZMYND3 antibody, p85 antibody, XETOR antibody, cbfa2t2-a antibody, CBFA2/RUNX1 translocation partner 2 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antibody, CBFA2/RUNX1 translocation partner 2 L homeolog antibody, Cbfa2t2 antibody, CBFA2T2 antibody, cbfa2t2.L antibody
- 背景
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Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8,21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Aliases: AML1 MTG8 antibody, cbfa2t2 antibody, Core binding factor runt domain alpha subunit 2 translocated to 2 antibody, core-binding factor, runt domain, alpha subunit 2 antibody, DKFZp313F2116 antibody, EHT antibody, ETO homolog on chromosome 20 antibody, ETO homologous on chromosome 20 antibody, MTG 8 like protein antibody, MTG 8 related protein 1 antibody, MTG8 like protein antibody, MTG8 related protein 1 antibody, MTG8-like protein antibody, MTG8-related protein 1 antibody, MTG8R_HUMAN antibody, MTGR 1 antibody, Myeloid translocation gene related protein 1 antibody, Myeloid translocation related protein 1 antibody, Myeloid translocation-related protein 1 antibody, p85 antibody, Protein CBFA2T2 antibody, ZMYND 3 antibody, ZMYND3 antibody
- UniProt
- O43439
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