CBFA2T2 抗体
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008].
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CBFA2T2
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
CBFA2T2
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
CBFA2T2
适用: 人
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our CBFA2T2 抗体
: "Novel binding partners of Ldb1 are required for haematopoietic development." in: Development (Cambridge, England), Vol. 133, Issue 24, pp. 4913-23, (2006) (PubMed).
Aliases for CBFA2T2 抗体
CBFA2/RUNX1 translocation partner 2 (Cbfa2t2) 抗体CBFA2/RUNX1 translocation partner 2 (CBFA2T2) 抗体
core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2) 抗体
CBFA2/RUNX1 translocation partner 2 L homeolog (cbfa2t2.L) 抗体
A430091M07 抗体
C330013D05Rik 抗体
cbfa2t2-a 抗体
Cbfa2t2h 抗体
EHT 抗体
MTGR1 抗体
p85 抗体
XETOR 抗体
ZMYND3 抗体
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