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CHEK2 抗体 (pThr68)
CHEK2
适用: 人, 小鼠, 大鼠
WB, ELISA, IF, IHC (p)
宿主: 兔
Polyclonal
unconjugated
CHEK2抗体详情
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抗原
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CHEK2
(Checkpoint Kinase 2 (CHEK2))
抗原表位
All epitopes for CHEK2 抗体
pThr68
适用
All reactivities for CHEK2 抗体
人, 小鼠, 大鼠
宿主
All hosts for CHEK2 抗体
兔
克隆类型
All clonalities for CHEK2 抗体
多克隆
标记
All conjugates for CHEK2 抗体
This CHEK2 antibody is un-conjugated
应用范围
All applications for CHEK2 抗体
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
CDS 1,Cds1,Cds1 homolog,Checkpoint kinase 2,Checkpoint like protein CHK2,CHEK 2,Chek2,Chk 2,CHK2 checkpoint homolog (S. pombe),CHK2 checkpoint homolog,CHK2,hCds1,HuCds 1,LFS 2,LFS2,PP1425,RAD 53,RAD53,Rad53 homolog,Serine/threonine protein kinase Chk2,Serine/threonine-protein kinase Chk2
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
亚型
IgG
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Alternatives
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使用细节
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应用备注
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
CHEK2目标详情
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抗原
CHEK2
(Checkpoint Kinase 2 (CHEK2))
别名
CHEK2 (CHEK2 产品 )
别名
CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
背景
Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
分子量
61kDa
基因ID
11200
UniProt
O96017
途径
p53 Pathway , Apoptosis , Cell Division Cycle
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