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TGFB1 抗体
TGFB1
适用: 人, 小鼠, 大鼠
IHC (p)
宿主: 小鼠
Monoclonal
10E5
unconjugated
TGFB1抗体详情
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抗原
See all TGFB1 抗体
TGFB1
(Transforming Growth Factor, beta 1 (TGFB1))
适用
All reactivities for TGFB1 抗体
人, 小鼠, 大鼠
宿主
All hosts for TGFB1 抗体
小鼠
克隆类型
All clonalities for TGFB1 抗体
单克隆
标记
All conjugates for TGFB1 抗体
This TGFB1 antibody is un-conjugated
应用范围
All applications for TGFB1 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
Cartilage-inducing factor,CED,Differentiation inhibiting factor,DPD1,LAP,Latency-associated peptide,Prepro transforming growth factor beta 1,TGF beta 1,TGF beta,TGF beta 1 protein,TGF-beta 1 protein,TGF-beta-1,TGF-beta-5,TGF-beta1,TGFB,Tgfb-1,tgfb1,TGFB1,TGFbeta,TGFbeta1,Transforming Growth Factor b1,Transforming Growth Factor beta 1,Transforming growth factor beta 1a,transforming growth factor beta-1,transforming growth factor,beta 1,Transforming Growth Factor-ß1
纯化方法
Protein A purification
免疫原
Synthetic Peptide of TGFbeta1
克隆位点
10E5
亚型
IgG
Top Product
Discover our top product TGFB1 Primary Antibody
Alternatives
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anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 351-390) antibody
TGFB1
适用: 人, 小鼠, 大鼠, 绵羊, 兔
WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody
TGFB1
适用: 小鼠, 大鼠, Cow, Pig, 绵羊, 豚鼠, 犬, 马, 山羊
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
IHC 1:100-200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
TGFB1目标详情
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抗原
TGFB1
(Transforming Growth Factor, beta 1 (TGFB1))
别名
TGFB1 (TGFB1 产品 )
别名
CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta5 antibody, ced antibody, dpd1 antibody, lap antibody, tgf-beta antibody, tgfb antibody, tgfb5 antibody, tgfbeta antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, ai39657 antibody, tgfb1 antibody, wu:fb13a07 antibody, xx:ai39657 antibody, TGFB1 antibody, csd antibody, cdb1 antibody, cdg2 antibody, csd1 antibody, csd2 antibody, csd3 antibody, ebmd antibody, lcd1 antibody, bigh3 antibody, cdgg1 antibody, betaig-h3 antibody, TGFB4 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor beta 1 L homeolog antibody, transforming growth factor, beta 1 antibody, transforming growth factor, beta 1a antibody, transforming growth factor beta induced L homeolog antibody, TGFB1 antibody, Tgfb1 antibody, tgfb1.L antibody, tgfb1a antibody, tgfbi.L antibody
背景
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
基因ID
7040
UniProt
P01137
途径
EGFR Signaling Pathway , Dopaminergic Neurogenesis , Cellular Response to Molecule of Bacterial Origin , Glycosaminoglycan Metabolic Process , Regulation of Leukocyte Mediated Immunity , Regulation of Muscle Cell Differentiation , Positive Regulation of Immune Effector Process , Cell-Cell Junction Organization , Production of Molecular Mediator of Immune Response , Ribonucleoside Biosynthetic Process , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Protein targeting to Nucleus , Autophagy , Cancer Immune Checkpoints
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