PIEZO1 抗体
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- 抗原 See all PIEZO1 抗体
- PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIEZO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 免疫原
- family with sequence similarity 38, member A
- 亚型
- IgG
- Top Product
- Discover our top product PIEZO1 Primary Antibody
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- 应用备注
- WB : 1:200-1:1000 IHC : 1:50-1:500
- 说明
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06435(Piezo1 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
- 别名
- Piezo1 (PIEZO1 产品)
- 别名
- DHS antibody, FAM38A antibody, Mib antibody, 9630020g22 antibody, Fam38a antibody, mKIAA0233 antibody, piezo type mechanosensitive ion channel component 1 antibody, piezo-type mechanosensitive ion channel component 1 antibody, PIEZO1 antibody, Piezo1 antibody
- 背景
- Synonyms:FAM38A, KIAA0233 Background:Pore-forming subunit of a mechanosensitive non-specific cation channel(PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling(PubMed:20016066). In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation(PubMed:25119035). Plays a key role in blood vessel formation and vascular structure in both development and adult physiology(By similarity).
- 分子量
- 250 kDa
- 基因ID
- 9780
- UniProt
- Q92508
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