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PIEZO1 抗体

PIEZO1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117527
发货至: 中国
  • 抗原 See all PIEZO1 抗体
    PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
    适用
    • 16
    • 11
    • 4
    • 2
    • 1
    人, 小鼠
    宿主
    • 10
    • 7
    克隆类型
    • 10
    • 7
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIEZO1 antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    family with sequence similarity 38, member A
    亚型
    IgG
    Top Product
    Discover our top product PIEZO1 Primary Antibody
  • 应用备注
    WB: 1:200-1:1000, IHC: 1:50-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
    别名
    Piezo1 (PIEZO1 产品)
    别名
    DHS antibody, FAM38A antibody, Mib antibody, 9630020g22 antibody, Fam38a antibody, mKIAA0233 antibody, piezo type mechanosensitive ion channel component 1 antibody, piezo-type mechanosensitive ion channel component 1 antibody, PIEZO1 antibody, Piezo1 antibody
    背景
    Synonyms:FAM38A, KIAA0233 Background:Pore-forming subunit of a mechanosensitive non-specific cation channel(PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling(PubMed:20016066). In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation(PubMed:25119035). Plays a key role in blood vessel formation and vascular structure in both development and adult physiology(By similarity).
    分子量
    250kd
    基因ID
    9780
    UniProt
    Q92508
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