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PIEZO1 抗体 (AA 2230-2420)

PIEZO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7163444
发货至: 中国
  • 抗原 See all PIEZO1 抗体
    PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    AA 2230-2420
    适用
    • 16
    • 12
    • 4
    • 2
    • 1
    宿主
    • 10
    • 7
    克隆类型
    • 10
    • 7
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIEZO1 antibody is un-conjugated
    应用范围
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Piezo-type mechanosensitive ion channel component 1 protein (2230-2420AA)
    亚型
    IgG
    Top Product
    Discover our top product PIEZO1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PIEZO1 (Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
    别名
    PIEZO1 (PIEZO1 产品)
    别名
    DHS antibody, FAM38A antibody, Mib antibody, 9630020g22 antibody, Fam38a antibody, mKIAA0233 antibody, piezo type mechanosensitive ion channel component 1 antibody, piezo-type mechanosensitive ion channel component 1 antibody, PIEZO1 antibody, Piezo1 antibody
    背景

    Background: Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling (PubMed:20016066). In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation (PubMed:25119035). Plays a key role in blood vessel formation and vascular structure in both development and adult physiology (By similarity).

    Aliases: DHS antibody, Fam38a antibody, Family with sequence similarity 38 member A antibody, KIAA0233 antibody, Membrane protein induced by beta-amyloid treatment antibody, Mib antibody, PIEZ1_HUMAN antibody, Piezo-type mechanosensitive ion channel component 1 antibody, PIEZO1 antibody, Protein FAM38A antibody, Protein FAM38B antibody, Protein PIEZO1 antibody

    UniProt
    Q92508
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