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HNRNPD/AUF1 抗体

HNRNPD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5703835
发货至: 中国
  • 抗原 See all HNRNPD/AUF1 (HNRNPD) 抗体
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    适用
    • 68
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    人, 小鼠, 大鼠
    宿主
    • 66
    • 2
    克隆类型
    • 67
    • 1
    多克隆
    标记
    • 38
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    This HNRNPD/AUF1 antibody is un-conjugated
    应用范围
    • 49
    • 30
    • 24
    • 23
    • 6
    • 4
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    免疫原
    heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
    亚型
    IgG
    Top Product
    Discover our top product HNRNPD Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab03950(HNRNPD antibody) at dilution of 1:500

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    别名
    HNRNPD (HNRNPD 产品)
    别名
    AUF1 antibody, AUF1A antibody, HNRPD antibody, P37 antibody, hnRNPD0 antibody, Auf1 antibody, Hnrnpd antibody, HNRNPD antibody, p37 antibody, auf1a antibody, hnrpd antibody, hnrnpd0 antibody, C230004L04 antibody, Hnrpd antibody, wu:fa28b06 antibody, zgc:162951 antibody, heterogeneous nuclear ribonucleoprotein D antibody, heterogeneous nuclear ribonucleoprotein D L homeolog antibody, HNRNPD antibody, Hnrnpd antibody, hnrnpd antibody, hnrnpd.L antibody
    背景
    Synonyms:AUF1,AUF1A,HNRPD,P37,hnRNPD0 Background:Binds with high affinity to RNA molecules that contain AU-rich elements(AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double-and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
    分子量
    38 kDa and 40 kDa
    基因ID
    3184
    UniProt
    Q14103
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