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HNRNPD/AUF1 抗体 (pSer83)

HNRNPD 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255528
发货至: 中国
  • 抗原 See all HNRNPD/AUF1 (HNRNPD) 抗体
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    抗原表位
    • 15
    • 10
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer83
    适用
    • 67
    • 28
    • 22
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 65
    • 2
    克隆类型
    • 66
    • 1
    多克隆
    标记
    • 37
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HNRNPD/AUF1 antibody is un-conjugated
    应用范围
    • 48
    • 29
    • 23
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-hnRPD (Ser83) Antibody detects endogenous levels of hnRPD only when phosphorylated at Ser83.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human hnRPD around the phosphorylation site of Ser83.
    亚型
    IgG
    Top Product
    Discover our top product HNRNPD Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    别名
    HNRNPD (HNRNPD 产品)
    别名
    AUF1 antibody, AUF1A antibody, HNRPD antibody, P37 antibody, hnRNPD0 antibody, Auf1 antibody, Hnrnpd antibody, HNRNPD antibody, p37 antibody, auf1a antibody, hnrpd antibody, hnrnpd0 antibody, C230004L04 antibody, Hnrpd antibody, wu:fa28b06 antibody, zgc:162951 antibody, heterogeneous nuclear ribonucleoprotein D antibody, heterogeneous nuclear ribonucleoprotein D L homeolog antibody, HNRNPD antibody, Hnrnpd antibody, hnrnpd antibody, hnrnpd.L antibody
    背景

    Description: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.

    Gene: HNRNPD

    分子量
    38 kDa
    基因ID
    3184
    UniProt
    Q14103
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