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- 抗原 See all COPS7B 抗体
- COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
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抗原表位
- AA 223-257
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS7B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应 （详细）
- Expected species reactivity: Bovine
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 223-257 from the human protein was used as the immunogen for the COPS7B antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product COPS7B Primary Antibody
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anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 1-157) antibody
COPS7B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 61-95) antibodyCOPS7B 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB56230 unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 1-264) antibodyCOPS7B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 223-257) antibodyCOPS7B 适用: 人 WB 宿主: 兔 Polyclonal RB56231 unconjugated
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- 应用备注
- Western blot: 1:500-1:1000
- 限制
- 仅限研究用
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- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the COPS7B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
- 别名
- COPS7B / CSN7b (COPS7B 产品)
- 别名
- MGC114836 antibody, D1Wsu66e antibody, E130114M23 antibody, CSN7B antibody, COP9 signalosome subunit 7B antibody, COP9 signalosome subunit 7B S homeolog antibody, Cops7b antibody, COPS7B antibody, cops7b.S antibody
- 背景
- COP9 signalosome complex subunit 7b is a component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- 基因ID
- 64708
- UniProt
- Q9H9Q2
- 途径
- Cell Division Cycle
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