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COPS7B 产品

(COP9 Signalosome Complex Subunit 7b (COPS7B))

Categories

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).

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Featured COPS7B Categories

COPS7B 抗体

High quality antibodies with extensive validation data.

COPS7B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COPS7B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7148503
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN6243119
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN528678
Quantity 50 μg
Datasheet Datasheet

Recommended COPS7B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350066
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3078408
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3125295
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to COPS7B

COP9 signalosome subunit 7B (Cops7b), COP9 signalosome subunit 7B (COPS7B), COP9 signalosome subunit 7B S homeolog (cops7b.S), CSN7B, D1Wsu66e, E130114M23, MGC114836

Protein level used designations for COPS7B

  • COP9 (constitutive photomorphogenic) homolog, subunit 7b
  • COP9 constitutive photomorphogenic homolog subunit 7B
  • COP9 signalosome complex subunit 7b
  • COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
  • COP9 constitutive photomorphogenic subunit 7B
  • COP9 complex S7b
  • JAB1-containing signalosome subunit 7b
  • SGN7b
  • signalosome subunit 7b
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