COPS7A 产品
(COP9 Signalosome Complex Subunit 7a (COPS7A))
Categories
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).
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Featured COPS7A Categories
Recommended COPS7A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7148499
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7148498
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7148497
Quantity
100 μL
Datasheet
Datasheet
Recommended COPS7A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6230625
Quantity
96 tests
Datasheet
Datasheet
Recommended COPS7A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350065
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3078456
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3128683
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to COPS7A
COP9 signalosome subunit 7A (COPS7A), COP9 signalosome subunit 7A (Cops7a), CSN7A, D6Ertd35eProtein level used designations for COPS7A
- COP9 (constitutive photomorphogenic), subunit 7a
- COP9 complex S7a
- COP9 signalosome complex subunit 7a
- JAB1-containing signalosome subunit 7a
- SGN7a
- signalosome subunit 7a
- COP9 complex subunit 7a
- COP9 constitutive photomorphogenic homolog subunit 7A
- dermal papilla-derived protein 10
- COP9 (constitutive photomorphogenic) homolog, subunit 7a
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